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Proteomics

Surname, First name Research Focus Availability
Hartl, Ulrich Research in Hartl and Hayer-Hartl laboratory focuses on the mechanisms of protein folding and quality control in the cell. Our goal is to reach a comprehensive understanding, at the structural and functional level, of how the machinery of molecular chaperones assists folding through the co­operation of co- and post-translational mechanisms. not available
Herms, Jochen Physiological function of proteins involved in Neurodegenerative diseases, synaptic failure in Neurodegenerative diseases like Alzheimer’s or Parkinson’s disease (AD,PD), long-term in vivo two-photon imaging of transgenic mice models of AD, neuronal calcium homeostasis in neurodegenerative diseases, high-throughput drug screens for AD and PD. not available
Imhof, Axel The overall goal of this project is to precisely characterize the molecular, morphological, and mechanistic context governing adenoviral gene expression to fully elucidate this efficiency. available in 2026
Kielkowski, Pavel Characterization of the cancer resistance protein bleomycin hydrolase (BLMH) using chemoproteomics available in 2026
Lichtenthaler, Stefan We study how Alzheimer’s disease develops in the brain on the molecular and cellular level. The aim of our research is to better understand the disease causes and to develop new diagnostic, therapeutic and preventive approaches. TBA
Nägele, Thomas Our aim is to reveal how photosynthesis and carbohydrate metabolism are stabilised in lavender plants under adverse growth conditions. available in 2026
Niessing, Dierk Our goal is to understand the molecular principles underlying cargo recognition by transport complexes, complex assembly and activation, and eventually complex disassembly after the transport. TBA
Robles, Maria While the circadian clock regulates metabolism, metabolic states, in turn, provide feedback to the circadian clock, modulating its function. We are investigating this molecular crosstalk in peripheral metabolic tissues from mice, employing interaction and spatial proteomics as well as phosphoproteomics. available in 2026
Sattler, Michael The student will contribute to the cloning of expression constructs, recombinant protein production, and purification, forming the foundation for the structural and functional studies. Through this work, we aim to uncover key aspects of the Grp94 functional cycle, providing insights that are fundamental for understanding ER proteostasis and may ultimately inform future drug discovery efforts targeting Grp94. available in 2026
Schmidt, Mathias V. We aim to elucidate the role of the chaperone protein FKBP51 (FK506-binding protein 51) in the regulation of EV release. available in 2026
Turck, Christoph W. The comparison of the proteome of diseased and healthy tissues and body fluids and the subsequent identification of the proteins that are different from normal in disease are pursued in order to unravel the pathogenesis of disease, to identify therapeutic targets, and to develop diagnostic tests. TBA