Helmholtz Center Munich, Institute of Stem Cell Research
Biomedical Center LMU Munich
LS Zellbiologie (Anatomie III)
+49 (0)89 / 2180-71633
Our research aims to elucidate the key mechanisms of neurogenesis in the developing and adult brain. In contrast to organs such as the skin, the small intestine or the hematopoietic system, most cells in the adult mammalian nervous system are permanently postmitotic, such as the neurons and the oligodendrocytes, and are not turned over nor regenerated once they die. Neurogenesis persists only in very few regions of the adult mammalian forebrain, and neurons degenerated after acute or chronic injury are not replaced in the adult mammalian brain. To overcome this, we study neurogenesis when and where it works with the aim to reactivate these mechanisms and re-instruct neurogenesis after brain injury.
Primary Technique(s): genetics, cell biology, biochemistry, imaging and molecular biology
Model Organism(s): Zebrafish