Amgen Scholars Program

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Developmental Biology

Surname, First name Research Focus Availability
Baier, Herwig The goal of our research is to understand how neuronal circuits convert sensory inputs into behavioral responses. not available
Herms, Jochen Physiological function of proteins involved in Neurodegenerative diseases, synaptic failure in Neurodegenerative diseases like Alzheimer’s or Parkinson’s disease (AD,PD), long-term in vivo two-photon imaging of transgenic mice models of AD, neuronal calcium homeostasis in neurodegenerative diseases, high-throughput drug screens for AD and PD. not available
Michalakis, Stylianos We have previously established a novel primary microglia culture protocol from mouse retina, which allows for good reproducibility, high cell numbers and long in vitro viability. In order to be able to efficiently manipulate retinal microglia in vivo and in vitro, efficient gene delivery technologies are needed. Within this project, we will evaluate novel-engineered adeno-associated virus (AAV) capsids regarding efficacy and specificity. These AAV variants will be tested in our mouse retinal microglia culture model, mouse retinal explant cultures and in a mouse model of retinal degeneration to validate their efficacy and specificity in vitro, ex vivo and in vivo. available
Ninkovic, Jovica We focus on basic and translational research in the field of the central nervous system (CNS) repair and regeneration aiming at novel strategies for brain repair and regeneration by modulating the function of glial cells. We aim at providing a basis for the development of new therapies for patients affected by stroke, neurotrauma or neurodegenerative diseases. not available